1-1 Animation Scene: Camera view starts with a stationary overhead, bisected microscopic view of the junction of the bile duct and hepatocyte cells via a canaliculus within the liver. These structures are flanked by capillary vessels on both sides with blood cells flowing through them, moving in an upper left to lower right motion. Bile acids are also shown in this initial camera view, moving through the canaliculus between hepatocyte cells as they progress towards the bile duct in a similar motion, from upper left to lower right. This stationary view is accented with a slight tilt and rotation, (superior to posterior) both at an approximate 45-degree angle.
Narration - "Tumor angiogenesis begins with the tumor targeting a nearby blood vessel."
1-2 Animation Scene: Camera view begins to slowly zoom in closer and closer while panning and rotating on individual bisected hepatocyte cells. An increased amount of bile acids is now being released from these hepatocyte cells, flowing through the canaliculus, and deposited into the bile duct. The speed of this camera zoom is gradual and constant.
Narration - "In fact, the process of bile acid synthesis..."
1-3 Animation Scene: Camera view movement concludes with a direct overhead view of the bisected hepatocytes showcasing a prominent, up close, zoomed in process of bile acid release, movement through the canaliculus and entrance into the bile duct. With this overhead position, the entire camera frame is filled with up close bisected structures, six hepatocytes, a canaliculus, a bile duct, and its junction point. All bisected hepatocyte and bile duct cells feature a nucleus at their central area.
Narration - "... is the body's most significant pathway for cholesterol catabolism."
1-4 Animation Scene: While maintaining this direct overhead view, camera movement now shifts to directly follow bile acids and their path through the canaliculus from a left to right movement. Camera speed gradually increases only slightly as the camera follows bile acids through canaliculus.
Narration - "Bile acids are transported into the..."
1-5 Animation Scene: As the direct overhead camera view follows bile acids through the canaliculus, a smooth, tight camera zoom is accompanied with a counterclockwise l /4 rotation resulting with the up-close view of a deep bile duct drop zone which is centrally positioned in a vertical orientation immediately before the bile acids are dropped deep into bile duct. Camera speed increases slightly while following bile acids dropping into bile duct, an action and movement analogous to a conveyor belt. With the camera view positioned from directly above, bile acids that are dropped are now followed by the camera view, placing the audience immediately behind dropped bile acids traveling through the bile duct.
Narration - "...canaliculi, gallbladder, and bile ducts... "
1-6 Animation Scene: With the camera view still oriented in a top/down position the bile acids continue to be followed through the bile duct with a slight clockwise rotation just before the bile duct comes to a terminal right turn. It is at this moment that a brief cut to black frame is added to indicate transition from bile duct to the gallbladder for storage, or to the small intestine to aid in digestion.
Narration - "...where they form mixed micelles with..."